반응 #61835

반응 방정식

1-(naphth-1-yl)-1-propanone

phenyltrimethylammonium tribromide

→

2-bromo-1-(naphth-1-yl)-1-propanone

수율 175.6%

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   기타then partitioned between petroleum ether and aqueous sodium carbonate solution
2. 2
   기타The organic layer was separated
3. 3
   세척washed with water, brine
4. 4
   건조dried with sodium sulphate
5. 5
   여과filtered
6. 6
   기타evaporated in vacuo

실험 절차

To a solution of 1-(naphth-1-yl)-1-propanone (4.0 g) in anhydrous tetrahydrofuran (50 ml) was added phenyltrimethylammonium tribromide (8.0 g). The resulting mixture was stirred overnight at room temperature then partitioned between petroleum ether and aqueous sodium carbonate solution. The organic layer was separated, washed with water, brine, dried with sodium sulphate, filtered and evaporated in vacuo to yield crude 2-bromo-1-(naphth-1-yl)-1-propanone (5.7 g).

출처