반응 #61833

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2-chloro-6-(trifluoromethyl)-1H-benzo[d]imidazole

8-amino-1,2,3,4-tetrahydronaphthalen-2-ol

→

title compound

8-(5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen -2-ol

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후처리

1. 1
   기타prepared
2. 2
   기타prepared

실험 절차

The reaction of 2-chloro-6-(trifluoromethyl)-1H-benzo[d]imidazole (154 mg, 0.7 mol, prepared according to the procedure described in WO 2004/035549 A1) with 8-amino-1,2,3,4-tetrahydronaphthalen-2-ol (83 mg, 0.5 mmol, prepared according to the procedure described in WO 2003/095420 A1) under the condition of Example 21(b) afforded the title compound. MS (ESI, pos. ion) m/z: 348 (M+1).

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