반응 #618041

ord-595bbbb8a1234873b920d7a43268b8de

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

A reaction mixture of 3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxylic acid (0.1 mmol, 49.5 mg), HCl salt of (3-amino-1-hydroxycyclohexyl)(phenyl)methanone (0.1 mmol, 25.5 mg), HATU (0.1 mmol, 38 mg) and DIEA (0.15 mL) in DMA (0.65 mL) was stirred at room temperature for overnight. The product, N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxamide, was obtained after rotary evaporation of solvent.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09351965B2uspto-grants-2016_05