반응 #616353

ord-5fbd7c38c66248e587ceea4b3a00c236

반응 방정식

O=[N+]([O-])c1ncccc1O
2-nitro-3-hydroxypyridine
O=C([O-])[O-].[K+].[K+]
potassium carbonate
CI
methyl iodide
→
COc1cccnc1[N+](=O)[O-]
title compound
수율 97.4%
COc1cccnc1[N+](=O)[O-]
3-methoxy-2-nitropyridine
수율 97.4%

반응물

O=[N+]([O-])c1ncccc1O
2-nitro-3-hydroxypyridine
O=C([O-])[O-].[K+].[K+]
potassium carbonate
CI
methyl iodide

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The similar reaction

실험 절차

The similar reaction as described in Reference Example 9 by using 2-nitro-3-hydroxypyridine (7.0 g), potassium carbonate (6.91 g) and methyl iodide (4.67 ml) gave the title compound (7.5 g) as crystalline powders.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09346822B2uspto-grants-2016_05