반응 #61432

반응 방정식

2-isopropoxy-5-methanesulfonyl-benzoic acid

2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride

→

title compound

2-[4-(2-Isopropoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzothiazole-4-carboxylic acid methyl ester

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   기타The crude material was purified by chromatography (SiO2, heptane/ethyl acetate)
2. 2
   기타the residue was then triturated in ether

실험 절차

Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride in tetrahydrofuran. The crude material was purified by chromatography (SiO2, heptane/ethyl acetate), and the residue was then triturated in ether to yield the title compound as a white solid.

출처