반응 #61362

반응 방정식

4-fluoronitrobenzene

2-thien-2-ylethanamine

K2CO3

→

N-(4-nitrophenyl)-N-(2-thien-2-ylethyl)amine

수율 93.8%

용매

N-methyl-pyrrolidinone

반응 조건

후처리

1. 1
   온도after cooling to room temperature
2. 2
   기타The yellow precipitate formed
3. 3
   여과was filtered off
4. 4
   건조dried over P2O5

실험 절차

2 g of 4-fluoronitrobenzene, 2.16 g of 2-thien-2-ylethanamine, and 2.35 g of K2CO3 were added to a solution of 20 ml of N-methyl-pyrrolidinone. The reaction medium was heated at 60° C. for 12 hours and, after cooling to room temperature, was then poured into a water+ice mixture. The yellow precipitate formed was filtered off, reslurried in water and then dried over P2O5. 3.3 g of N-(4-nitrophenyl)-N-(2-thien-2-ylethyl)amine (1) were obtained.

출처