반응 #6131

반응 방정식

sodium methylate

4-nitrophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside

→

expected product

수율 81.1%

4-nitrophenyl 5-thio-β-D-xylopyranoside

수율 81.1%

용매

methanol

methanol

반응 조건

후처리

1. 1
   workup.ADDITIONAfter complete solubilization (2 h), the reaction mixture is neutralized by the addition of Amberlite® IR 120 H+ resin
2. 2
   여과filtered

실험 절차

0.2 ml of a solution of sodium methylate in methanol (8% w/v of Na) is added under an inert atmosphere to a suspension of 1.1 g (2.6.10-3 mol) of 4-nitrophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside in 30 ml of methanol. After complete solubilization (2 h), the reaction mixture is neutralized by the addition of Amberlite® IR 120 H+ resin and then filtered. 620 mg (yield: 79%) of the expected product are obtained after evaporation to dryness and lyophilization.

출처