반응 #61032

반응 방정식

4-(4-Cyano-2,3-difluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

trifluoroacetic acid

→

title compound

2,3-Difluoro-4-piperazin-1-yl-benzonitrile trifluoro-acetic acid

용매

dichloromethane

반응 조건

후처리

1. 1
   농축After such time the reaction mixture was concentrated in vacuo

실험 절차

To a solution of 4-(4-Cyano-2,3-difluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (0.72 g) in dichloromethane (5 mL) was added trifluoroacetic acid and the reaction mixture was stirred at room temperature for 30 minutes. After such time the reaction mixture was concentrated in vacuo to yield the title compound (0.63 g). MS (m/e): 224.3 (M+H+, 100%).

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