반응 #609528

반응 방정식

Sodium carboxylate

sodium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

triphenylsulfonium chloride

→

objective material

수율 40.0%

triphenylsulfonium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

수율 40.0%

용매

methylene chloride

반응 조건

후처리

1. 1
   기타The organic layer was separated
2. 2
   추출the aqueous layer was extracted with CH2Cl2
3. 3
   세척the combined organic layers were washed three times with H2O
4. 4
   workup.DISTILLATIONThe solvent was distilled off under reduced pressure

실험 절차

Sodium carboxylate (21) obtained in (Synthesis Example 1-1-2) was dissolved in 20 g of methylene chloride, 40 g of an aqueous solution of triphenylsulfonium chloride (22) was added to the solution and the resulting mixture was stirred for 30 minutes. The organic layer was separated, the aqueous layer was extracted with CH2Cl2, and the combined organic layers were washed three times with H2O. The solvent was distilled off under reduced pressure to obtain 4.6 g of the objective material, onium salt (Q-1) (Yield: 40%).

출처