반응 #60951

ord-fc1203deeb0949a888ece709f3315086

반응 방정식

CNS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1
2-Chloro-5-methylsulfamoyl-benzoic acid
O=C(O)c1cc(S(=O)O)ccc1Cl
2-Chloro-5-sulfino-benzoic acid
NCC1CC1
cyclopropylmethylamine
O=C(O)c1cc(S(=O)(=O)NCC2CC2)ccc1Cl
title compound
수율 81.0%
O=C(O)c1cc(S(=O)(=O)NCC2CC2)ccc1Cl
2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid
수율 81.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타obtained in 81% yield

실험 절차

The title compound was synthesised according to the procedure described for 2-Chloro-5-methylsulfamoyl-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and cyclopropylmethylamine and obtained in 81% yield. MS (m/e): 288.0 (MH−, 100%).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07427612B2uspto-grants-2008_09