반응 #608265
ord-47086fea0aa24b8d8c6857cd612a9563
반응 방정식
3-amino-4-fluoro-benzoic acid
cis-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline
2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate
→
title compound
수율 47.0%
(3-Amino-4-fluoro-phenyl)-(cis-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-methanone
수율 47.0%
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
The title compound is prepared from 3-amino-4-fluoro-benzoic acid and cis-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1 [2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate is used]. Yield: 47% of theory; LC (method 4): tR=1.94 min; Mass spectrum (ESI+): m/z=325 [M+H]+.