반응 #60816

ord-4ba0fc3093b642a380e91fa81ffc746d

반응 방정식

Cn1cnc(-c2ccccc2)c1CO
Intermediate 1
Cn1cnc(-c2ccccc2)c1CO
(1-methyl-4-phenyl-1H-imidazol-5-yl)methanol
COc1ccc(CN)cc1
4-methoxybenzylamine
COC(C=O)OC
dimethoxyacetaldehyde
COc1ccc(Cn2cnc(-c3ccccc3)c2C(OC)OC)cc1
title compound
COc1ccc(Cn2cnc(-c3ccccc3)c2C(OC)OC)cc1
5-(Dimethoxymethyl)-1-(4-methoxybenzyl)-4-phenyl-1H-imidazole

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared by a similar process to that described for preparation of Intermediate 1, except that 4-methoxybenzylamine was used in place of methylamine and dimethoxyacetaldehyde in place of glycolaldehyde. Colourless oil (1.5 g, 74%);

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07427616B2uspto-grants-2008_09