반응 #60810
ord-bfa91bba01444c858e262522dcf3c6d5
반응 방정식
sodium thiomethoxide
6-methyl-4-chlorothieno[3,2-d]pyrimidine
→
title compound
수율 97.0%
6-Methyl-4-(methylthio)thieno[3,2-d]pyrimidine
수율 97.0%
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과The mixture was filtered
- 2세척the solid was washed with acetonitrile
- 3기타The combined filtrate and washes were evaporated
실험 절차
A solution of sodium thiomethoxide (24S mg) and 6-methyl-4-chlorothieno[3,2-d]pyrimidine (Acta Pol. Pharm. (1986), 43(2), 97-100) (650 mg) in acetonitrile (50 mL) was stirred overnight. The mixture was filtered and the solid was washed with acetonitrile. The combined filtrate and washes were evaporated to give the title compound as a white solid (665 mg, 97%);