반응 #6072

반응 방정식

maleic anhydride

phenyl vinyl sulfide

ethylaluminum dichloride

→

title compound

수율 90.7%

2,4-dioxo-6-phenylthio-3-oxabicyclo[3.2.0]heptane

수율 90.7%

용매

1,2-dichloroethane

methylene chloride

반응 조건

후처리

1. 1
   세척The methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution
2. 2
   건조once with brine, dried over anhydrous sodium sulfate
3. 3
   농축concentrated

실험 절차

To a solution of maleic anhydride (0.39 g, 4 mmol) and phenyl vinyl sulfide (0.52, 4 mmol) in 17 mL of 1,2-dichloroethane under nitrogen, was added 2 mL (0.5 equiv) of ethylaluminum dichloride. The resultant solution was stirred at ambient temperature for 0.5 h and then diluted with 75 mL of methylene chloride. The methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution and once with brine, dried over anhydrous sodium sulfate and concentrated to give 0.85 g of the title compound; EI-MS, m/e (rel intensity): 234 (M+, 23), 136 (100), 109 (12), 91 (21).

출처