반응 #6024

반응 방정식

methyl 4-hydroxy-3-propenylbenzoate

potassium carbonate

allyl bromide

→

title compound

수율 87.0%

methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate

수율 87.0%

용매

acetone

반응 조건

후처리

1. 1
   여과The mixture was filtered through Celite
2. 2
   세척the filter cake was washed with more acetone and dichloromethane
3. 3
   기타After removing the solvents
4. 4
   workup.DISTILLATIONthe resulting oil was distilled under high vacuum

실험 절차

A solution of 3.04 g (15.8 mmol) of methyl 4-hydroxy-3-propenylbenzoate (Example 42, Step B) was refluxed with anhydrous potassium carbonate (4.37 g, 2 equiv) and allyl bromide (3.5 mL, 2.5 equiv) in acetone overnight. The mixture was filtered through Celite and the filter cake was washed with more acetone and dichloromethane. After removing the solvents, the resulting oil was distilled under high vacuum to give 3.2 g (87%) of the title compound.

출처