반응 #600689

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2-methyl-quinolin-8-ylamine

2-methyl-8-aminoquinoline

Intermediate 22

2-methyl-8-aminoquinoline

4-methoxy-2-nitrobenzenesulfonyl chloride

→

title compound

수율 51.8%

2-Nitro-4-methoxy-N-(2-methyl-quinolin-8-yl)-benzenesulfonamide

수율 51.8%

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실험 절차

In a similar fashion using route 14 general procedure 27, 2-methyl-quinolin-8-ylamine (Intermediate 22) (500 mg, 3.1 mmol) and 4-methoxy-2-nitrobenzenesulfonyl chloride (826 mg, 3.4 mmol) and DMAP (19 mg, 1.5 mmol) gave the title compound (600 mg, 51%).

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