반응 #600648

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2-methyl-8-aminoquinoline

Intermediate 22

2-methyl-8-aminoquinoline

benzenesulfonyl chloride

→

title compound

수율 43.0%

N-(2-Methylquinolin-8-yl)-benzenesulfonamide

수율 43.0%

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실험 절차

In the similar fashion using route 14 general procedure 27, 2-methyl-8-aminoquinoline (Intermediate 22) (200 mg, 1.2 mmol), benzenesulfonyl chloride (230 mg, 1.2 mmol) and DMAP (cat.) gave the title compound (150 mg, 43%) after purification by column chromatography with DCM as the eluent.

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