반응 #5996

반응 방정식

phenol

(RS)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-5-hydroxy -6-methoxy-3-isoquinolinecarboxylic acid, ethyl ester

4-methoxy-3-methyl benzyl chloride

→

(RS)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy -5-[(4-methoxy-3-methylphenyl)methoxy]-3-isoquinolinecarboxylic acid, ethyl ester

반응 조건

후처리

1. 1
   기타The product is purified by silica gel chromatography

실험 절차

This compound is prepared from the phenol derivative of Example 31 and 4-methoxy-3-methyl benzyl chloride by a procedure similar to that in Example 32. The product is purified by silica gel chromatography; tlc (1:1 ethyl-acetate/hexane), one spot, Rf 0.7.

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