반응 #59926

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( 6f )

2-(((4-((2-methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethanol

→

title compound

수율 5.5%

2-(((3-methyl-4-(2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

수율 5.5%

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후처리

1. 1
   기타obtained in the step (35a)

실험 절차

The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethanol obtained in the step (35a) to obtain the title compound (163 mg, total yield: 5.5%) as a light yellow solid.

출처