반응 #595351

반응 방정식

compound

2-(4-Chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole-5-carboxylic acid

trimethylsilyldiazomethane

→

Methyl 2-(4-chlorophenyl)-4-[(methoxymethoxy)methyl]-1,3-oxazole-5-carboxylate

용매

toluene

hexane

methanol

반응 조건

후처리

1. 1
   기타the solvent is then removed on a rotary evaporator
2. 2
   기타The residue is used without further purification in the subsequent reaction

실험 절차

138 mg (0.52 mmol) of the compound from Example 42A are dissolved in 3 ml toluene and 2.5 ml of methanol. 0.4 ml (0.79 mmol) of a 2 M solution of trimethylsilyldiazomethane in hexane is then added dropwise. The mixture is stirred at RT for 10 min and the solvent is then removed on a rotary evaporator. The residue is used without further purification in the subsequent reaction.

출처