반응 #5908

반응 방정식

Hydrazine hydrate

3-[4-(4-oxo-1,4-dihydropyridin-1-yl)benzoyl]butanoic acid

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title compound

5-Methyl-6-[4-(4-oxo-1,4-dihydropyridin-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone

용매

water

반응 조건

후처리

1. 1
   온도under reflux for 2 hours
2. 2
   온도cooled

실험 절차

Hydrazine hydrate (1.8 g) was added to a suspension of 3-[4-(4-oxo-1,4-dihydropyridin-1-yl)benzoyl]butanoic acid (5 g) in water (60 ml). The resulting solution was stirred under reflux for 2 hours and cooled to afford the title compound as a pale yellow solid, 4.45 g, m.p. 255°-258° C.

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