반응 #59072

반응 방정식

3-(tert-butyl)phenylamine

sodium bicarbonate

thiophosgene

→

3-(tert-butyl)benzenisothiocyanate

용매

acetone

반응 조건

후처리

1. 1
   기타was brought to ambient temperature
2. 2
   농축concentrated
3. 3
   기타partitioned between ethyl acetate and water
4. 4
   건조The organic layer was dried with sodium bicarbonate and sodium sulfate
5. 5
   농축concentrated

실험 절차

To 3-(tert-butyl)phenylamine in acetone at 0° C. was added sodium bicarbonate (2 eq) and thiophosgene (2 eq). The mixture was brought to ambient temperature and concentrated and partitioned between ethyl acetate and water. The organic layer was dried with sodium bicarbonate and sodium sulfate and concentrated to yield 3-(tert-butyl)benzenisothiocyanate. MS: MH+=192.

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