반응 #59024

ord-4e49a290cc6449e9b2491cdda45e1841

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타the solvent was evaporated under reduced pressure
  2. 2
    세척The residue was washed with water

실험 절차

Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. 2 mol/L hydrochloric acid (1.09 mL) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07423185B2uspto-grants-2008_09