반응 #58920

반응 방정식

4-nitrobenzaldehyde

1,3-thiazolidine-2,4-dione

piperidine

→

5-(4-nitrobenzylidene)-1,3-thiazolidine-2,4-dione

수율 59.2%

용매

ethanol

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도under reflux for 24 hrs
3. 3
   농축The reaction mixture was concentrated
4. 4
   세척The obtained residue was washed with ethanol

실험 절차

A mixture of 4-nitrobenzaldehyde (15.1 g), 1,3-thiazolidine-2,4-dione (11.70 g), piperidine (1.70 g) and ethanol (300 mL) was heated under reflux for 24 hrs. The reaction mixture was concentrated. The obtained residue was washed with ethanol to give 5-(4-nitrobenzylidene)-1,3-thiazolidine-2,4-dione as yellow crystals (14.8 g, yield 59%). Recrystallization thereof from acetone-hexane gave pale-yellow prism crystals. melting point: 272-273° C.

출처