반응 #58863

반응 방정식

K2CO3

pentynol

t-butyldiphenylsilylchloride

Et3N

→

t-butylpent-4-ynyloxy diphenyl silane

수율 98.0%

용매

CH2Cl2

반응 조건

후처리

1. 1
   추출extracted with CH2Cl2
2. 2
   건조The combined extracts are dried over MgSO4
3. 3
   농축concentrated in vacuo
4. 4
   여과The residue is purified by filtration on a silica pad

실험 절차

A mixture of pentynol (8.0 g, 95 mmol), t-butyldiphenylsilylchloride (28 g, 114 mmol) and Et3N (14 g, 138 mmol) in CH2Cl2 is stirred at room temperature for 16 h, treated with 1M K2CO3 and extracted with CH2Cl2. The combined extracts are dried over MgSO4 and concentrated in vacuo. The residue is purified by filtration on a silica pad to obtain 30 g of t-butylpent-4-ynyloxy diphenyl silane (yield: 98%

출처