반응 #587763

반응 방정식

dibenzofuran

trioxane

bromide

→

bromide

2-Bromomethyl-dibenzofuran

용매

acetic acid

HBr

반응 조건

후처리

1. 1
   농축concentrated
2. 2
   workup.DISSOLUTIONthe residue was dissolved in CH2Cl2
3. 3
   세척washed with water
4. 4
   건조dried over Na2SO4
5. 5
   기타evaporated

실험 절차

A mixture of dibenzofuran (93.5 g, 0.557 M), trioxane (20 g, 0.222 M) and myrystyltrimethylammonium bromide (6.2 g, 18.5 mmol) in 1 L acetic acid and 135 mL of 48% HBr was stirred at 50-60° C. for 28 h, then concentrated; the residue was dissolved in CH2Cl2, washed with water, dried over Na2SO4, evaporated to give the crude bromide 1a. Compound 1a was used without further purification in the next step.

출처