반응 #58747

반응 방정식

(5-Bromo-pyridin-3-yl)-methanol

→

title compound

수율 51.1%

5-Bromo-pyridine-3-carbaldehyde

수율 51.1%

반응 조건

후처리

1. 1
   온도The reaction mixture was heated
2. 2
   온도at reflux temperature for 3 h
3. 3
   여과The hot reaction mixture was filtered through a pad of diatomaceous earth
4. 4
   농축the filtrate was concentrated

실험 절차

(5-Bromo-pyridin-3-yl)-methanol (1.13 g, 6.00 mmol) was dissolved in CHCI3 (40 mL) and treated with MnO2 (3.60 g). The reaction mixture was heated at reflux temperature for 3 h. The hot reaction mixture was filtered through a pad of diatomaceous earth and the filtrate was concentrated to yield the title compound (0.570 g, 51%).

출처