반응 #58631

반응 방정식

3-pyridylacetone

5-Chloro-2-choromethylpyridine

phenylacetone

4-chlorobenzyl bromide

→

2-Amino-4-(5-chloro-2-pyridyl)-3-phenylbutane hydrochloride salt

반응 조건

실험 절차

5-Chloro-2-choromethylpyridine (Weidmann, K. et al. J. Med. Chem. 1992, 35, 438) and phenylacetone were used in place of 4-chlorobenzyl bromide and 3-pyridylacetone in Step A of Reference Example 4. LC-MS: m/e 261 (M+H)+.

출처