반응 #5854

반응 방정식

N,N'-bis-(2,6-diisopropylphenyl) guanidine

α,α-dibromo-p-xylene

potassium carbonate

→

white powder

수율 39.1%

N,N'-bis-(2,6-diisopropylphenyl)-N"-(4-bromomethylphenyl) methylguanidine

수율 39.1%

용매

toluene

반응 조건

후처리

1. 1
   온도The thus-formed mixture was then refluxed
2. 2
   온도under heating for 10 hours
3. 3
   온도to cool
4. 4
   기타the insoluble substance was removed by filtration
5. 5
   세척The thus-obtained filtrate was washed with water
6. 6
   농축the concentrated for the purpose
7. 7
   기타of recovering the solvent
8. 8
   기타to obtain a slightly brown powder
9. 9
   기타The powder was then recrystallized from acetone

실험 절차

11.4 g (0.03 mole) of N,N'-bis-(2,6-diisopropylphenyl) guanidine, 8.7 g (0.03 mole) of α,α-dibromo-p-xylene and 2.1 g (0.015 mole) of anhydrous potassium carbonate were added to 50 ml of toluene. The thus-formed mixture was then refluxed under heating for 10 hours. After the mixture had been allowed to cool, the insoluble substance was removed by filtration. The thus-obtained filtrate was washed with water and the concentrated for the purpose of recovering the solvent to obtain a slightly brown powder. The powder was then recrystallized from acetone to obtain 6.6 g of white powder.

출처