반응 #5853

반응 방정식

N,N'-bis-(2,6-diisopropylphenyl) guanidine

α,α-dichloro-m-xylene

potassium carbonate

→

white powder

수율 32.8%

N,N'-bis-(2,6-diisopropylphenyl)-N"-(3-chloromethylphenyl) methylguanidine

수율 32.8%

용매

xylene

반응 조건

후처리

1. 1
   온도The thus-formed mixture was then refluxed
2. 2
   온도under heating for 10 hours
3. 3
   온도to cool
4. 4
   기타the insoluble substance was removed by filtration
5. 5
   세척The thus-obtained filtrate was washed with water
6. 6
   농축concentrated for the purpose
7. 7
   기타of recovering the solvent and unreacted raw materials
8. 8
   기타to obtain a slightly yellow crystal
9. 9
   기타The crystal was then recrystallized from acetone

실험 절차

11.4 g (0.03 mole) of N,N'-bis-(2,6-diisopropylphenyl) guanidine, 5.7 g (0.033 mole) of α,α-dichloro-m-xylene and 2.1 g (0.015 mole) of anhydrous potassium carbonate were added to 50 ml of xylene. The thus-formed mixture was then refluxed under heating for 10 hours. After the mixture had been allowed to cool, the insoluble substance was removed by filtration. The thus-obtained filtrate was washed with water and then concentrated for the purpose of recovering the solvent and unreacted raw materials to obtain a slightly yellow crystal. The crystal was then recrystallized from acetone to obtain 5.1 g of white powder.

출처