반응 #582510

반응 방정식

sodium hydroxide

ammonium chloride

pentafluorobenzenesulfonyl chloride

→

pentafluorobenzenesulfonamide

용매

acetone

반응 조건

후처리

1. 1
   workup.ADDITIONDuring addition, pH
2. 2
   여과Precipitated product was filtered
3. 3
   기타recrystallized from toluene

실험 절차

To an aqueous solution of ammonium chloride was added dropwise an acetone solution of pentafluorobenzenesulfonyl chloride at room temperature. During addition, pH was adjusted to 7 by an aqueous sodium hydroxide solution. Precipitated product was filtered and recrystallized from toluene to give pentafluorobenzenesulfonamide. The structure was confirmed by 1H-NMR, 19F-NMR and IR.

출처