반응 #58017

반응 방정식

6-bromohexanol

THF

cinnamoyl chloride

→

6-bromohexyl cinnamate

수율 53.0%

용매

triethylamine

반응 조건

후처리

1. 1
   기타at 0° C
2. 2
   여과The resultant was filtered
3. 3
   기타to remove the solvent
4. 4
   기타the residue was purified with a SiO2 column chromatography (EA:n-Hexane=1:5)

실험 절차

7 g of 6-bromohexanol was dissolved in a mixed solution of 5 ml of triethylamine as base and 50 ml of THF, and then, cinnamoyl chloride was added dropwise thereto at 0° C. The resultant was filtered to remove the solvent and the residue was purified with a SiO2 column chromatography (EA:n-Hexane=1:5) to obtain 8 g of 6-bromohexyl cinnamate (yield: 53%).

출처