반응 #578431

반응 방정식

triphenylsulfonium chloride

sodium 1,1-difluoro-2-tosyloxyethanesulfonate

→

triphenylsulfonium 1,1-difluoro-2-tosyloxyethanesulfonate

수율 74.0%

용매

dichloromethane

반응 조건

후처리

1. 1
   기타synthesized in Synthesis Example 9
2. 2
   기타The organic layer was separated
3. 3
   세척washed with 20 g of water three times
4. 4
   농축The organic layer was concentrated
5. 5
   workup.ADDITION10 g of diisopropyl ether was added to the residue for crystallization
6. 6
   여과The crystals were filtered
7. 7
   기타dried
8. 8
   기타obtaining the target compound

실험 절차

To 62 g of dichloromethane were added an amount (corresponding to 0.031 mole) of the triphenylsulfonium chloride aqueous solution of Synthesis Example 1 and 1.1 g (0.033 mole) of sodium 1,1-difluoro-2-tosyloxyethanesulfonate synthesized in Synthesis Example 9, followed by stirring. The organic layer was separated and washed with 20 g of water three times. The organic layer was concentrated and 10 g of diisopropyl ether was added to the residue for crystallization. The crystals were filtered and dried, obtaining the target compound. White crystals, 1.3 g (yield 74%).

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