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(2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone

4-Trifluoromethyl-benzenesulfonyl chloride

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title compound

N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]4-trifluoromethyl-benzenesulfonamide

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실험 절차

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone and 122 mg of 4-Trifluoromethyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.31 (d, 1H, J=2.8 Hz), 7.36 (m, 2H), 7.54-7.59 (m, 2H), 7.73 (d,1H, J=8.0 Hz), 7.77 (d, 1H, J=9.2 Hz), 7.97 (d, 1H, J=8.0 Hz), 8.00 (s, 1H), 8.82 (dd, 2H, J=6.0 Hz, 1.2 Hz), 10.16 (s, 1H). MS: m/z 441.8 (M++1).

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