반응 #5741
ord-0b945865b6ed43e89b1d0e52682f9023
반응 방정식
n-dodecyl alcohol
chlorosulfonyl isocyanate
→
white solid
수율 101.6%
Dodecyl(chlorosulfonyl)carbamate
수율 101.6%
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1농축concentrated in vacuo
- 2기타The residue was triturated with cold hexanes
- 3기타to give a white solid
- 4여과collected by filtration
실험 절차
A solution of n-dodecyl alcohol (10.7 g, 57.4 mmoles) in 100 mL Et2O was added dropwise to a solution of chlorosulfonyl isocyanate (5.0 mL, 57.4 mmoles) in 100 mL Et2O at ~15° C. under an atmosphere of N2. The resulting mixture was stirred for 2 hours and concentrated in vacuo. The residue was triturated with cold hexanes to give a white solid and collected by filtration to give 19.12 g of a white solid, mp 62°-63° C.