반응 #5739

반응 방정식

[1,1':3',1"-terphenyl]-2'-yl (chlorosulfonyl)carbamate

n-dodecyl alcohol

triethylamine

→

title compound

수율 42.5%

[1,1':3',1"-Terphenyl]-2'-yl[(dodecyloxy)sulfonyl]carbamate

수율 42.5%

용매

THF

THF

반응 조건

후처리

1. 1
   농축concentrated in vacuo
2. 2
   기타partitioned between H2O and EtOAc
3. 3
   건조The EtOAc layer was dried with MgSO4
4. 4
   기타evaporated
5. 5
   기타to give a white solid

실험 절차

A solution of [1,1':3',1"-terphenyl]-2'-yl (chlorosulfonyl)carbamate (5.0 g, 12.9 mmoles) in 75 mL THF was added dropwise to a solution of n-dodecyl alcohol (2.4 g, 12.9 mmoles) and triethylamine (1.3 g, 12.9 mmoles) in 100 mL THF at ~15° C. under an atmosphere of N2. The mixture was allowed to warm to room temperature for 16 hours, then concentrated in vacuo and partitioned between H2O and EtOAc. The EtOAc layer was dried with MgSO4 and evaporated to give a white solid. Chromatography (SiO2, 10% EtOAc/hexanes) gave 2.95 g of the title compound, mp 124°-126° C.

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