반응 #57223

ord-55fd26b9def14fdfbeb77186c62ed165

반응 방정식

Cc1ccc(S(=O)(=O)n2ccc3c(-c4oc(C)nc4-c4ccc(N)cc4)ccnc32)cc1
4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-oxazol-4-yl)aniline
CN(C)C(=O)Cl
dimethylcarbamoyl chloride
Cc1ccc(S(=O)(=O)n2ccc3c(-c4oc(C)nc4-c4ccc(NC(=O)N(C)C)cc4)ccnc32)cc1
title product
Cc1ccc(S(=O)(=O)n2ccc3c(-c4oc(C)nc4-c4ccc(NC(=O)N(C)C)cc4)ccnc32)cc1
N,N-dimethyl-N′-[4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-oxazol-4-yl)phenyl]urea

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Following the procedure described for Intermediate 31 with 4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-oxazol-4-yl)aniline and dimethylcarbamoyl chloride provided the title product. ESMS[M+H]+: 516.2

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07419988B2uspto-grants-2008_09