반응 #569996

반응 방정식

4-hydroxy-4'-biphenylcarboxylic acid

(-)2-methylbutanol

sulfuric acid

→

4-hydroxy-4'-biphenylcarboxylic acid 2-methylbutyl ester

용매

benzene

반응 조건

후처리

1. 1
   온도heated in a container
2. 2
   기타provided with a Dean-Stark
3. 3
   온도reflux condenser
4. 4
   기타Generated water was removed
5. 5
   온도After the reaction mother liquor was cooled
6. 6
   세척washed with water
7. 7
   workup.DISTILLATIONthe solvent was distilled off

실험 절차

20 g of 4-hydroxy-4'-biphenylcarboxylic acid, 53 g of (-)2-methylbutanol, and 4 g of conc. sulfuric acid were refluxed for 20 minutes, admixed with 500 ml of benzene, and heated in a container provided with a Dean-Stark reflux condenser. Generated water was removed. After the reaction mother liquor was cooled and washed with water, the solvent was distilled off to obtain crude 4-hydroxy-4'-biphenylcarboxylic acid 2-methylbutyl ester. The product was recrystallized from benzene-heptane mixed solvent to obtain a purified product having a melting point of 115° to 116° C.

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