반응 #569380
ord-0c327a62b7d647198fc2bf36d377b55c
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도The solution was cooled in an ice bath
- 2세척washed with 0.5N HCl solution, twice with a saturated sodium bicarbonate solution and finally with distilled water
- 3건조The solvent was dried over magnesium sulphate
- 4여과filtered through silica
- 5농축concentrated to dryness
실험 절차
To a stirred solution of decanol (6.0 g, 7.23 mmol) in dichloromethane (150 ml) was added dry pyridine (3.66 ml, 45.6 mmol). The solution was cooled in an ice bath. To this was added 1-chloroethyl chloroformate (6.5 g, 45.6 mmol) dropwise. The reaction mixture was allowed to proceed overnight, diluted with dichloromethane and washed with 0.5N HCl solution, twice with a saturated sodium bicarbonate solution and finally with distilled water. The solvent was dried over magnesium sulphate, filtered through silica and concentrated to dryness.