반응 #569232

반응 방정식

N-chloroacetyl-N-ethoxycarbonylmethyl-4-(2,2,3,3-tetrafluoropropoxy)aniline

ammonia ethanol

→

1-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-2,5-piperazinedione

반응 조건

후처리

1. 1
   온도After cooling
2. 2
   기타the crystals separated
3. 3
   여과rated out therefrom were collected by filtration
4. 4
   세척washed with cold ethanol

실험 절차

The resulting N-chloroacetyl-N-ethoxycarbonylmethyl-4-(2,2,3,3-tetrafluoropropoxy)aniline (1.9 g) was dissolved in 20 ml of 10.5% ammonia-ethanol and the solution was stirred at 60° C. for four hours. After cooling, the crystals separated rated out therefrom were collected by filtration and washed with cold ethanol to give 1.5 g of 1-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-2,5-piperazinedione as colorless crystals.

출처