반응 #56878

반응 방정식

4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine

4-chloro-phenylamine

→

title compound

수율 76.0%

6-(5-Bromo-2-methyl-phenyl)-N*4*-(4-chloro-phenyl)-pyrimidine-2,4-diamine

수율 76.0%

반응 조건

실험 절차

Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-chloro-phenylamine provided the title compound (76% yield). 1H NMR (DMSO-d6) δ 2.35 (s, 3H, CH3), 6.39 (s, 1H, Ar), 7.40 (d, 1H, J=8.4 Hz, Ar), 7.47 (d, 2H, J=8.5 Hz, Ar), 7.70-7.71 (m, 2H, Ar), 7.84-7.89 (m, 2H, Ar), 10.95 (br s, 1H, NH).

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