반응 #567176

반응 방정식

3-fluoronitrobenzene

1-methylpiperazine

→

1-(3-Nitrophenyl)4-methylpiperazine

반응 조건

후처리

1. 1
   기타The cooled mixture was purified by column-chromatography on silica gel using
2. 2
   workup.ADDITIONa mixture of ethyl acetate and methanol (9:1 v/1) as the eluent

실험 절차

A mixture of 3-fluoronitrobenzene (20 ml; 0.19 mol) and 1-methylpiperazine (40 ml; 0.36 mol) was heated to 120° C. for a week. The cooled mixture was purified by column-chromatography on silica gel using a mixture of ethyl acetate and methanol (9:1 v/1) as the eluent. Yield: 33 g (79%).

출처