반응 #566669

ord-c9157a86b4ed409d9595a9d8e0593589

반응 방정식

CC[C@H](C)[C@H](N)C(=O)O
(L)-Isoleucine
Cc1ccc(C(=O)Cl)cc1
p-toluoyl chloride
→
CC[C@@H](C)[C@@H](NC(=O)c1ccc(C)cc1)C(=O)O
desired product
CC[C@@H](C)[C@@H](NC(=O)c1ccc(C)cc1)C(=O)O
(2R,3R)-3-methyl-2-((4-methylbenzoyl)amino)pentanoic Acid

반응물

CC[C@H](C)[C@H](N)C(=O)O
(L)-Isoleucine
Cc1ccc(C(=O)Cl)cc1
p-toluoyl chloride

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

(L)-Isoleucine and p-toluoyl chloride were processed as described in Example 26A to provide the desired product.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06645968B2uspto-grants-2003_11