반응 #56581

반응 방정식

2,3,5-Triiodobenzoyl chloride

1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane

triethylamine

→

1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane

용매

methylene chloride

반응 조건

후처리

1. 1
   농축The mixture was concentrated
2. 2
   기타purified by flash chromatography (ethyl acetate/hexane)

실험 절차

2,3,5-Triiodobenzoyl chloride (1.54 g, 3.08 mmol) was added to a mixture of 1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane (1 g, 2.97 mmol) and triethylamine (1 ml) in methylene chloride (80 ml) and the resulting mixture stirred overnight at room temperature under nitrogen. The mixture was concentrated and purified by flash chromatography (ethyl acetate/hexane) to yield 1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane.

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