반응 #565292

반응 방정식

hydrogen

aniline

2-heptanone

4-toluene sulphonic acid

→

N-(1methylhexyl)aniline

수율 37.0%

용매

ethyl acetate

반응 조건

후처리

1. 1
   기타The cooled reaction mixture
2. 2
   여과filtered
3. 3
   세척washed with 1N-hydrochloric acid (6×200 parts) and water (2×200 parts)
4. 4
   기타the ethyl acetate was separated
5. 5
   건조dried (MgSO4)
6. 6
   기타before evaporating

실험 절차

A mixture of aniline (100 parts), 2-heptanone (220 parts), 4-toluene sulphonic acid (6 parts) and 3% palladium on carbon (5 parts) in a 1 litre autoclave was charged with hydrogen to a pressure of 80 atmospheres and heated at 150° C. for 40 hours. The cooled reaction mixture was diluted with ethyl acetate, filtered, washed with 1N-hydrochloric acid (6×200 parts) and water (2×200 parts), the ethyl acetate was separated and dried (MgSO4) before evaporating to leave N-(1methylhexyl)aniline (76 parts, 37%).

출처