반응 #56518

반응 방정식

9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate

hydroxylamine hydrochloride

sodium formate

→

9-Hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carbonitrile

용매

formic acid

반응 조건

후처리

1. 1
   온도is refluxed for 30 hrs
2. 2
   기타The product crystallize
3. 3
   온도on cooling
4. 4
   여과is filtered
5. 5
   세척washed with acetone

실험 절차

A mixture of 9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate (1 mm), hydroxylamine hydrochloride (1.3 mm) and sodium formate (2 mm) is refluxed for 30 hrs. in formic acid (3 parts). The product crystallize on cooling, is filtered and washed with acetone. The dry crystals are light beige, m.p. 289°-92° C.

출처