반응 #564542

ord-f59a2217abf242fe8512ca2f37af668b

반응 방정식

CC[O-].[Na+]
sodium ethylate
CCOC(=O)C(=CC=C(C(=S)OCC)N(C)C)c1ccccc1
diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate
CCOC(=O)C(=CC=[N+](C)C)N(C)C.F[B-](F)(F)F
N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate
CCOC(=O)CSC
ethyl (methylthio)acetate
→
CCOC(=O)C(C)=CC=C(C(=S)OCC)N(C)C
Diethyl 2-dimethylamino-5-methylthio-2,4-hexadienedioate

반응물

CC[O-].[Na+]
sodium ethylate
CCOC(=O)C(=CC=C(C(=S)OCC)N(C)C)c1ccccc1
diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate
CCOC(=O)C(=CC=[N+](C)C)N(C)C.F[B-](F)(F)F
N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate
CCOC(=O)CSC
ethyl (methylthio)acetate
—
ethanolic solution

시약

없음

용매

CCO
ethanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The procedure is as in Example 2 for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (28.6 g), a 2M ethanolic solution of sodium ethylate (50 cc) and ethyl (methylthio)acetate (13.4 g) in ethanol (180 cc). Diethyl 2-dimethylamino-5-methylthio-2,4-hexadienedioate (21.9 g) is thereby obtained in the form of a brown oil, and is used in the crude state in the subsequent syntheses.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04886835uspto-grants-1989_12