반응 #564379

반응 방정식

6-(4-hydroxyimino-1-piperidylcarbonyl)-3,4-dihydrocarbostyril

acetic anhydride

triethylamine

→

6-(4-acetyloxyimino-1-piperidylcarbonyl)-3,4-dihydrocarbostyril

용매

methylene chloride

반응 조건

후처리

1. 1
   추출extracted with chloroform
2. 2
   추출The chloroform extract
3. 3
   건조was dried with anhydrous sodium carbonate
4. 4
   기타the solvent was removed by evaporation

실험 절차

15 Grams of 6-(4-hydroxyimino-1-piperidylcarbonyl)-3,4-dihydrocarbostyril, 11.4 ml of acetic anhydride and 31.8 ml of triethylamine in 300 ml of methylene chloride solution were mixed together and stirred at room temperature overnight. The reaction mixture was poured into ice-water, and extracted with chloroform. The chloroform extract was dried with anhydrous sodium carbonate, then the solvent was removed by evaporation to yield 16.5 g of 6-(4-acetyloxyimino-1-piperidylcarbonyl)-3,4-dihydrocarbostyril.

출처