반응 #564084

반응 방정식

3-methyl-2-chloroquinoline

hydrazine hydrate

→

2-hydrazino-3-methylquinoline

반응 조건

후처리

1. 1
   온도under reflux for 3 hours
2. 2
   온도The reaction mixture is cooled
3. 3
   여과the solid is filtered off
4. 4
   세척washed
5. 5
   기타dried
6. 6
   기타The crystalline mass obtained
7. 7
   기타is recrystallized from isopropanol

실험 절차

73.5 g of 3-methyl-2-chloroquinoline in 102 ml of hydrazine hydrate are heated under reflux for 3 hours. The reaction mixture is cooled and the solid is filtered off, washed and dried. The crystalline mass obtained is recrystallized from isopropanol to give 50.5 g of 2-hydrazino-3-methylquinoline melting at 128° C.

출처