반응 #56367

반응 방정식

phenylbenzoin

phenylbenzoin

hydroxylamine

sodium acetate

hydroxylamine hydrochloride

hydroxylamine

phenylbenzoin

→

alpha-phenylbenzoin oxime

수율 40.0%

용매

methanol

water

반응 조건

후처리

1. 1
   기타round bottomed flask fitted with a reflux condenser
2. 2
   기타was prepared
3. 3
   workup.ADDITIONby treating 177.9 g
4. 4
   workup.ADDITIONwas added
5. 5
   온도The solution was cooled
6. 6
   여과filtered
7. 7
   workup.ADDITIONtreated with refluxing hexane
8. 8
   workup.WAITAfter 72 hours the solid remaining in the extraction thimble
9. 9
   기타was collected

실험 절차

180 g (0.625 mole) of phenylbenzoin was added to a 3 liter, one necked, round bottomed flask fitted with a reflux condenser and a nitrogen bypass. 1.45 liters of methanol was added to dissolve the phenylbenzoin and free hydroxylamine was prepared by treating 177.9 g. (2.56 moles) hydroxylamine hydrochloride with 209.9 g (2.56 moles) of sodium acetate in water. The resultant solution was added to the phenylbenzoin and the reaction mixture was stirred for 48 hours at reflux at which time an additional 1.24 moles of hydroxylamine was added. The solution was cooled and filtered. The solids were then placed in a Soxhlet extractor and treated with refluxing hexane. After 72 hours the solid remaining in the extraction thimble was collected to yield 40% of the theoretical yield of pure alpha-phenylbenzoin oxime, m.p. 150°-52° C. (lit. 153.5) The hexane extract can be concentrated to yield unreacted phenylbenzoin (50% of theory) which may be recycled to afford additional phenylbenzoin oxime. This material was employed to polymerize 2,6-xylenol using the following composition:

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